Denis Noble

Denis Noble

Department of Physiology, Anatomy and Genetics; University of Oxford

Professor Emeritus and co-Director of Computational Physiology at Oxford University. One of the pioneers of Systems Biology and developed the first viable mathematical model of the working heart in 1960. Over 350 articles in academic journals, including Nature, Science, PNAS, Journal of Physiology.

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Denis was Chairman of the IUPS (International Union of Physiological Sciences) World Congress in 1993, and Secretary-General of IUPS from 1993-2001. He is now President. His Previous publications include the seminal set of essays The Logic of Life (Boyd and Noble, OUP 1993), and he played a major role in launching the Physiome Project, one of the international components of the systems biology approach. Science magazine included him amongst its review authors for its issue devoted to the subject in 2002



".... all the central assumptions of the Modern Synthesis (often also called Neo-Darwinism) have been disproved. Moreover, they have been disproved in ways that raise the tantalizing prospect of a totally new synthesis..."

(Physiology is rocking the foundations of evolutionary biology, p.1235)