John S. Torday

John S. Torday

Departments of Pediatrics and Ob/Gyn, Evolutionary Medicine Program, David Geffen School of Medicine; University of California- Los Angeles

Professor and Director, The Henry L. Guenther Laboratory for Cellular-Molecular Biology at Harbor-UCLA. Foundational studies of the molecular basis for lung alveolar structure and function; first to determine the molecular basis for integrated physiologic alveolar function, 1995. Author of over 150 peer-reviewed papers, 18 on the cellular basis of vertebrate physiologic evolution from its unicellular origins to complex structure and function.

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John has Chaired 5 symposia in the U.S. and Germany on the cellular origins of vertebrate physiology. His latest Review Article in Perspectives in Biology  and Medicine, Evolutionary Biology Redux, starts with the premise that physiology and medicine are descriptive rather than mechanistic, obviating the possibility of hypothesis testing experimental evidence for evolution. This is due to the scant attention to cellular biology and cellular dynamics' of cell biology in Evolution Theory. By starting from the unicellular origins of life, moving forward, the origins of complex physiology become transparent, offering the possibility of a Central Theory of Biology.

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"The purpose of this book is to understand the why and how of evolution by focusing on the cell as the smallest unit of biologic structure and function. The consensus is that unicellular organisms developed the complete genetic toolkit for the evolution of multicellular organisms. Multicellular organisms, in turn, evolved form and function in adaptation to their environments through metabolic cooperativity."

(Evolutionary Biology, Cell-Cell Communication and Complex Disease)

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