Michael J. Joyner

Michael J. Joyner

Frank R. and Shari Caywood Professor of Anesthesiology, Mayo Clinic;

The laboratory of Michael J. Joyner, M.D., is interested in how humans respond to various forms of physical and mental stress during activities such as exercise, hypoxia, standing up and blood loss.

Dr. Joyner and his team study how the nervous system regulates blood pressure, heart rate and metabolism in response to these forms of stress. They are also interested in how blood flow to muscle and skin responds to these stressors. These responses are studied in young healthy subjects, healthy older subjects and people with conditions such as heart failure.

Finally, Dr. Joyner is personally interested in the role of integrative approaches in science as a powerful tool to integrate and critique data from reductionist approaches.

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By studying normal physiology and how it is affected by aging, sex and disease, Dr. Joyner and his colleagues gain insight into what body systems are potential therapeutic targets for intervention. Their research also provides insight into the many complex mechanisms that operate together to keep us healthy and able to adapt to the demands of life — or fail in a way that makes us unable to adapt.

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